Lorenzo's Oil (1992)

A busy executive learns during a meeting that his mother may be dying and rushes home to her side. He ends up being his father's caretaker and becomes closer to him than ever before. Estranged from his own son, the executive comes to realize what has been missing in his own life.

When Christy discovers her 10-year-old daughter Anna has a rare, incurable disease, she becomes a ferocious advocate for her daughter’s healing as she searches for a solution. After Anna has a freak accident and falls three stories, a miracle unfolds in the wake of her dramatic rescue that leaves medical specialists mystified, her family restored and their community inspired.

Working-class father John Crowley is finally on the fast track to corporate success when his two young children are diagnosed with Pompe disease—a condition that prevents the body from breaking down sugar. With the support of his wife, John ditches his career and teams with unconventional specialist, Dr. Robert Stonehill to found a bio-tech company and develop a cure in time to save the lives of his children. As Dr. Stonehill works tirelessly to prove the theories that made him the black sheep of the medical community, a powerful bond is forged between the two unlikely allies.

Wealthy American housewife Mary Morgan takes her bullied son George out of school for home education,including a trip to Southern Africa. Whilst in Mozambique George is bitten by a mosquito which crawls through a hole in his net and dies of malaria. After his funeral at home Mary feels a compulsion to return to Africa where she meets English woman Martha O'Connell,whose 24 year old son Ben, a teacher with voluntary service overseas,has also died of malaria. Ben gave his net to one of his pupils,believing adults cannot catch malaria. The two women are shocked to see the high death rate caused by the disease and,whilst Martha stays in Africa as a voluntary helper,Mary petitions the American government to change things. Martha turns up at Mary's house unannounced and,helped by Mary's ex-diplomat father,they address a senate committee on health spending,persuading them to do more to combat malaria. They meet with some success though a coda states that much more can be done.

Jackie Foster, a dynamic Assistant District Attorney and single mom, is looking forward to wrapping up her latest case and spending Christmas with Gracie, her adorable and precocious, eight-year old daughter. But when Jackie’s estranged dad, Jack , a gruff retired police officer, unexpectedly shows up at her door, they will be forced to confront old wounds.

James White is a troubled twentysomething trying to stay afloat in a frenzied New York City. As he retreats further into a hedonistic lifestyle, his mother's battle with a serious illness faces a series of setbacks that force him to assume more responsibility. With the pressure on him mounting, James must find new reserves of strength or risk imploding completely.

12-year-old Conor encounters an ancient tree monster who proceeds to help him cope with his mother's terminal illness and being bullied in school.

For ten years, engineer Bill Markham has searched tirelessly for his son Tommy who disappeared from the edge of the Brazilian rainforest. Miraculously, he finds the boy living among the reclusive Amazon tribe who adopted him. And that's when Bill's adventure truly begins. For his son is now a grown tribesman who moves skillfully through this beautiful-but-dangerous terrain, fearful only of those who would exploit it. And as Bill attempts to "rescue" him from the savagery of the untamed jungle, Tommy challenges Bill's idea of true civilization and his notions about who needs rescuing.

NASA must devise a strategy to return Apollo 13 to Earth safely after the spacecraft undergoes massive internal damage putting the lives of the three astronauts on board in jeopardy.

A bitterly divided family is forced to cooperate when their holiday plane crash-lands in the California wilderness. Overcoming their differences, they concentrate on repairing the plane and attempt to build a makeshift runway which will help them escape the unforgiving terrain.

Twenty-year-old Maria is a troubled and lonely girl who falls in love with the grounded and patient Adam. He is the first boyfriend to treat her nicely, but Maria struggles with her past and the relationship with her dad, who left her when she was very young. When her dad reappears it makes Maria vulnerable to the fear of being rejected once again.

A fatally ill mother with only two months to live creates a list of things she wants to do before she dies without telling her family of her illness.

A master thief coincidentally is robbing a house where a murder—in which the President of the United States is involved—occurs in front of his eyes. He is forced to run, while holding evidence that could convict the President.

When Martin, a former GDR citizen, is released from jail, he lately becomes confronted with the consequences of the German re-unification.

After moving to a new town, troublemaking teen Jim Stark is supposed to have a clean slate, although being the new kid in town brings its own problems. While searching for some stability, Stark forms a bond with a disturbed classmate, Plato, and falls for local girl Judy. However, Judy is the girlfriend of neighborhood tough, Buzz. When Buzz violently confronts Jim and challenges him to a drag race, the new kid's real troubles begin.

A young transgender man explores his gender identity and searches for love in rural Nebraska.